Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061196 | 0.87 | CA12 (0.52) | CA12CA1CA2CA4CA9 | |
| SCHEMBL20100621 | 0.84 | CA12 (0.50) | CA12CA1CA2CA4CA9 | |
| SCHEMBL22667659 | 0.82 | CA12 (0.48) | CA12CA1CA2CA4CA9 | |
| SCHEMBL10181438 | 0.82 | CA12 (0.48) | CA12CA1CA2CA4CA9 | |
| SCHEMBL22683217 | 0.81 | CA12 (0.48) | CA12CA1CA2CA4CA9 | |
| SCHEMBL25315672 | 0.77 | LMNA (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL20589908 | 0.77 | KDM5A (0.44) | CA12CA1CA2CA4CA9 | |
| SCHEMBL25336856 | 0.77 | CA12 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5346712 | 0.76 | TSHR (0.52) | CA12CA1CA2CA4CA9 | |
| SCHEMBL27386844 | 0.75 | CA12 (0.37) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081459-A1 | MESSENGER RIBONUCLEIC ACIDS FOR ENHANCING IMMUNE RESPONSES AND METHODS OF USE THEREOF | MODERNATX, INC. (US) | 2018-05-03 | — | — | WO | disclosed |