Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 8/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23426287 | 0.99 | GNAI3 (0.51) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19040739 | 0.99 | GNAI3 (0.51) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19032620 | 0.99 | GNAI3 (0.51) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19040735 | 0.99 | GNAI3 (0.51) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19040754 | 0.97 | GNAI3 (0.52) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL22920299 | 0.94 | GNAI3 (0.49) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19032551 | 0.93 | GNAI3 (0.46) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL25364803 | 0.92 | GNAI3 (0.51) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL21421515 | 0.91 | GNAI3 (0.43) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19040674 | 0.91 | GNAI3 (0.43) | GNAI3GNAO1GNAI1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458590-B9 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3458590-B1 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-01-27 | — | — | EP | disclosed |
| WO-2018081459-A1 | MESSENGER RIBONUCLEIC ACIDS FOR ENHANCING IMMUNE RESPONSES AND METHODS OF USE THEREOF | MODERNATX, INC. (US) | 2018-05-03 | — | — | WO | disclosed |