Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691037 | 1.00 | CYP3A4 (0.41) | CYP3A4CA1CA2CA4KMT2A | |
| SCHEMBL7752634 | 0.77 | CYP3A4 (0.32) | CYP3A4MAPT | |
| SCHEMBL21247206 | 0.75 | — | — | |
| SCHEMBL108518 | 0.75 | — | — | |
| SCHEMBL3432699 | 0.74 | MAPT (0.32) | CYP3A4MAPT | |
| SCHEMBL1397843 | 0.74 | MAPT (0.32) | CYP3A4MAPT | |
| SCHEMBL3072970 | 0.73 | CYP3A4 (0.38) | CYP3A4KMT2AMAPT | |
| SCHEMBL1861015 | 0.71 | MAPT (0.30) | CYP3A4MAPT | |
| SCHEMBL1713338 | 0.71 | MAPT (0.34) | CYP3A4MAPT | |
| SCHEMBL8056826 | 0.71 | MAPT (0.34) | CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749659-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |
| EP-3045443-B1 | METHOD FOR PRODUCING -CYCLOLAVANDULAL AND DERIVATIVE OF SAME | SHINETSU CHEMICAL CO (JP) | 2018-05-02 | — | — | EP | disclosed |