Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777564 | 0.98 | CYP3A4 (0.39) | CYP3A4MEN1ALDH1A1KMT2APTPN1 | |
| SCHEMBL569284 | 0.75 | — | — | |
| SCHEMBL20100996 | 0.73 | CYP3A4 (0.41) | CYP3A4KMT2AMAPT | |
| SCHEMBL2691037 | 0.73 | CYP3A4 (0.41) | CYP3A4KMT2AMAPT | |
| SCHEMBL1397843 | 0.71 | MAPT (0.32) | CYP3A4MAPT | |
| SCHEMBL3432699 | 0.71 | MAPT (0.32) | CYP3A4MAPT | |
| SCHEMBL1743456 | 0.71 | APLNR (0.40) | ALDH1A1MAPT | |
| SCHEMBL1132822 | 0.71 | TLR4 (0.32) | ALDH1A1MAPT | |
| SCHEMBL7752634 | 0.70 | CYP3A4 (0.32) | CYP3A4MAPT | |
| SCHEMBL16516842 | 0.68 | APLNR (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152686-B1 | HYDROXY SULFONATE OF QUINONE COMPOUNDS AND THEIR USES | ARQULE INC (US) | 2014-12-17 | — | — | EP | disclosed |
| US-7790765-B2 | Hydroxy sulfonate of quinone compounds and their uses | ARQULE, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090028952-A1 | Hydroxy sulfonate of quinone compounds and their uses | ARQULE, INC. | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028952-A1 | Hydroxy sulfonate of quinone compounds and their uses | SQOR, SULT1E1, NQO1 | CYP3A4 293/4885MEN1 2314/4885ALDH1A1 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.