SCHEMBL20101561

SCHEMBL20101561

Cc1ccc(C(SCCN)(c2ccccc2)c2ccc(C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14945645 1.00 KIF11 (1.00) KIF11
SCHEMBL13485497 0.89 KIF11 (0.89) KIF11
SCHEMBL38315 0.89 KIF11 (1.00) KIF11
Hydrochloric Acid SCHEMBL34901 0.87 KIF11 (0.96) KIF11
SCHEMBL14962369 0.85 KIF11 (0.74) KIF11
SCHEMBL23720124 0.84 KIF11 (0.70) KIF11
SCHEMBL12417490 0.81 KIF11 (1.00) KIF11
Cysteamine SCHEMBL3970283 0.80 KIF11 (0.81) KIF11
SCHEMBL19543229 0.79 KIF11 (0.66) KIF11
SCHEMBL825812 0.79 KIF11 (0.67) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180120326-A1 METHODS FOR DETECTING RENAL DISEASE IDEXX LABORATORIES, INC. 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180120326-A1 METHODS FOR DETECTING RENAL DISEASE ABAT, SLC1A5, DAO KIF11 4437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.