Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384514 | 0.88 | TSHR (0.50) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL997848 | 0.86 | TSHR (0.39) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9221919 | 0.85 | TSHR (0.36) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL3176460 | 0.85 | TSHR (0.36) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20412050 | 0.84 | TDP1 (0.46) | TDP1SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL18705903 | 0.84 | TSHR (0.50) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL28259378 | 0.84 | TSHR (0.50) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL1186550 | 0.84 | TSHR (0.42) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL29336223 | 0.82 | SMN1; SMN2 (0.41) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL40032 | 0.82 | ALDH1A1 (0.47) | TDP1SMN1; SMN2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155502-A1 | ORGANOSILICON COMPOUNDS HAVING AMINO ACID MOIETIES, AND PROCESS FOR PREPARATION THEREOF | WACKER CHEMIE AG (DE) | 2018-06-07 | — | — | US | disclosed |
| US-20180118889-A1 | METHOD FOR PRODUCING ORGANOSILICON COMPOUNDS HAVING AMINO ACID GROUPS | WACKER CHEMIE AG (DE) | 2018-05-03 | — | — | US | disclosed |