Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.50 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.50 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091029 | 0.87 | MAPT (0.54) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28866215 | 0.83 | CYP1A1 (0.59) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29428410 | 0.83 | MAPT (1.00) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL998182 | 0.83 | MAPT (1.00) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL20101688 | 0.81 | CYP1A2 (0.57) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17178286 | 0.80 | CYP3A4 (0.48) | MAPTRAB9AALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL15314622 | 0.79 | MAPT (0.71) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28803629 | 0.79 | MAPT (0.76) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL12880138 | 0.78 | MAPT (0.75) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29512056 | 0.78 | MAPT (0.75) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081672-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-03 | — | — | WO | disclosed |
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | UNIV CALIFORNIA (US) | 2018-05-03 | — | — | US | disclosed |
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | UNIV CALIFORNIA (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | EPHA2, L1CAM, ERBB2 | MAPT 3715/4885MEN1 2277/4885KMT2A 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.