Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ESRRB | O95718 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESRRA | P11474 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690324 | 0.90 | LMNA (0.53) | LMNAMAPTALDH1A1SUV39H2SMN1; SMN2 | |
| SCHEMBL24379385 | 0.89 | MAPT (0.56) | LMNAMAPTALDH1A1SUV39H2SMN1; SMN2 | |
| SCHEMBL16622221 | 0.84 | MAPT (0.52) | LMNAMAPTALDH1A1SUV39H2SMN1; SMN2 | |
| SCHEMBL31630879 | 0.82 | MAPT (0.55) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15863100 | 0.82 | MAPT (0.58) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20046702 | 0.82 | LMNA (0.52) | LMNAMAPTALDH1A1SUV39H2SMN1; SMN2 | |
| SCHEMBL16597605 | 0.81 | MAPT (0.54) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12331686 | 0.81 | MAPT (0.56) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30180045 | 0.81 | MAPT (0.56) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28681685 | 0.81 | MAPT (0.51) | LMNAMAPTALDH1A1SUV39H2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118943-A1 | PH SENSITIVE FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2018-05-03 | — | — | US | disclosed |