SCHEMBL20102222

SCHEMBL20102222

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4cc5ccccc5c5ccccc45)cc3)c3ccc(-c4cc5ccccc5c5ccccc45)cc3)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
PDK2 Q15119 3/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
MPI P34949 1/20 0.31
KMT2A Q03164 1/20 0.31
NISCH Q9Y2I1 1/20 0.31
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392412 1.00 CYP11B1 (0.35) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL24221729 0.99 CYP11B1 (0.34) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL22107922 0.96 CYP11B1 (0.35) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL21969229 0.96 GPR84 (0.33) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL22669934 0.96 CYP11B1 (0.35) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL23448081 0.96 CYP11B1 (0.35) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL23820671 0.96 CYP11B1 (0.35) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL23448090 0.96 CYP11B1 (0.35) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL20102238 0.96 PDK2 (0.34) CYP11B1GPR84PDK2ALDH1A1HPGD
SCHEMBL21392414 0.95 GPR84 (0.32) CYP11B1GPR84PDK2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2023-06-21 EP disclosed
WO-2023085878-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed
US-20220029101-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2022-01-27 US disclosed
US-20210359223-A1 ORGANIC LIGHT-EMITTING ELEMENT LG CHEM, LTD. (KR) 2021-11-18 US disclosed
US-20200365814-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2020-11-19 US disclosed
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-03 US disclosed
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210359223-A1 ORGANIC LIGHT-EMITTING ELEMENT LAS1L, ARL1, NAP1L4 CYP11B1 1620/4885GPR84 2553/4885PDK2 3587/4885
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME OR10J3, BMI1, ETV6 CYP11B1 1121/4885GPR84 3448/4885PDK2 2148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.