SCHEMBL20102241

SCHEMBL20102241

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccc5oc6ccc(-c7ccccc7)cc6c5c4)cc3)c3cc4ccccc4c4ccccc34)cc21

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDK2 Q15119 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17126415 0.96 HSP90AA1 (0.33)
SCHEMBL20102264 0.96 HSP90AA1 (0.33)
SCHEMBL17126750 0.94 PLA2G2A (0.34) PLA2G2APLA2G4AKDM4EALDH1A1MAPT
SCHEMBL9916307 0.94 PLA2G2A (0.34) PLA2G2APLA2G4AKDM4EALDH1A1MAPT
SCHEMBL10110068 0.94 PLA2G2A (0.34) PLA2G2APLA2G4AKDM4EALDH1A1MAPT
SCHEMBL9916628 0.94 PLA2G2A (0.34) PLA2G2APLA2G4AKDM4EALDH1A1MAPT
SCHEMBL14295370 0.93 HSP90AA1 (0.31) KDM4EALDH1A1MAPTHPGDPGR
SCHEMBL14295378 0.93 HSP90AA1 (0.31) KDM4EALDH1A1MAPTHPGDPGR
SCHEMBL17126428 0.93 HSP90AA1 (0.33) PLA2G2APLA2G4AKDM4EALDH1A1MAPT
SCHEMBL9916658 0.93 PLA2G2A (0.34) PLA2G2APLA2G4AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-03 US disclosed
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME OR10J3, BMI1, ETV6 PLA2G2A 4388/4885PLA2G4A 4595/4885KDM4E 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.