Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919977 | 0.84 | HCRTR1 (0.58) | HCRTR1HCRTR2RAB9ANPC1LMNA | |
| SCHEMBL2012177 | 0.84 | HCRTR1 (0.58) | HCRTR1HCRTR2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2011775 | 0.84 | HCRTR1 (0.58) | HCRTR1HCRTR2RAB9ANPC1LMNA | |
| SCHEMBL2014746 | 0.81 | HCRTR1 (0.61) | HCRTR1HCRTR2RAB9ANPC1PADI4 | |
| SCHEMBL2015191 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2RAB9ANPC1KMT2A | |
| SCHEMBL13139060 | 0.80 | HCRTR1 (0.77) | HCRTR1HCRTR2RAB9ANPC1KMT2A | |
| SCHEMBL2011910 | 0.80 | HCRTR1 (0.69) | HCRTR1HCRTR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2012888 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2RAB9ANPC1MEN1 | |
| SCHEMBL2015844 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2RAB9ANPC1MEN1 | |
| SCHEMBL2016685 | 0.80 | HCRTR1 (0.66) | HCRTR1HCRTR2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |