SCHEMBL20102467

SCHEMBL20102467

CCOc1ccc2c(c1F)-c1c-2cc(OCC2CCCC2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.37
SLC6A4 P31645 1/20 0.36
HTR6 P50406 1/20 0.36
C5AR1 P21730 1/20 0.35
KDM1A O60341 2/20 0.35
APOBEC3G Q9HC16 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
COL1A1 P02452 1/20 0.34
FFAR1 O14842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111285 0.91 HPGD (0.36) PTGDR2KDM1AALDH1A1HPGDFFAR1
SCHEMBL20111270 0.91 HPGD (0.36) PTGDR2KDM1AALDH1A1HPGDFFAR1
SCHEMBL20102392 0.90 HTR2A (0.34) PTGDR2KDM1A
SCHEMBL20111289 0.89 SLC6A4 (0.35) SLC6A4HTR6C5AR1HPGD
SCHEMBL20102396 0.87 HTR2A (0.32) PTGDR2KDM1AHPGD
SCHEMBL20111299 0.87 BRD4 (0.35) ALDH1A1FFAR1
SCHEMBL20111547 0.86 HTR2A (0.32) PTGDR2KDM1A
SCHEMBL20117898 0.85 HPGD (0.39) SLC6A4HTR6C5AR1HPGDFFAR1
SCHEMBL1500529 0.84 SLC6A4 (0.43) SLC6A4HTR6APOBEC3GALDH1A1LMNA
SCHEMBL20111371 0.84 HTR2A (0.31) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed
EP-3315583-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S PTGDR2 1255/4885SLC6A4 2219/4885HTR6 2692/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S PTGDR2 1255/4885SLC6A4 2219/4885HTR6 2692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.