Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205261 | 0.94 | P2RX7 (0.45) | P2RX7GAAMEN1CASP6KMT2A | |
| SCHEMBL18208556 | 0.89 | P2RX7 (0.42) | P2RX7HSD11B1 | |
| SCHEMBL18208710 | 0.89 | P2RX7 (0.42) | P2RX7HSD11B1 | |
| SCHEMBL18208494 | 0.82 | P2RX7 (0.45) | P2RX7GAAMEN1CASP6KMT2A | |
| SCHEMBL18209085 | 0.82 | KMT2A (0.42) | P2RX7GAAMEN1CASP6KMT2A | |
| SCHEMBL18208519 | 0.80 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL18208520 | 0.80 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL18208191 | 0.80 | P2RX7 (0.44) | P2RX7HSD11B1 | |
| SCHEMBL18208912 | 0.79 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL18208621 | 0.78 | NPC1 (0.49) | P2RX7GAAMEN1CASP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078005-A1 | AMIDO-SUBSTITUTED AZASPIRO DERIVATIVES AS TANKYRASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |