Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103535 | 0.88 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL12191933 | 0.88 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL12191936 | 0.88 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL2504416 | 0.85 | OPRD1 (0.48) | FFAR1 | |
| SCHEMBL29454583 | 0.85 | OPRD1 (0.48) | FFAR1 | |
| SCHEMBL18501542 | 0.85 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL2501419 | 0.85 | OPRD1 (0.48) | FFAR1 | |
| SCHEMBL18501544 | 0.85 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL30533375 | 0.85 | OPRD1 (0.48) | FFAR1 | |
| SCHEMBL29454615 | 0.85 | OPRD1 (0.48) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |