Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103203 | 0.86 | SMYD3 (0.44) | PDE4BHPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL18208278 | 0.84 | PDE4B (0.41) | PDE4BHPGDCRHR1CRHR2KMT2A | |
| SCHEMBL18208276 | 0.84 | PDE4B (0.41) | PDE4BHPGDCRHR1CRHR2KMT2A | |
| SCHEMBL18208502 | 0.83 | IRAK4 (0.49) | KDM4EHSD17B10 | |
| SCHEMBL18208548 | 0.83 | IRAK4 (0.49) | KDM4EHSD17B10 | |
| SCHEMBL18209065 | 0.83 | IRAK4 (0.49) | KDM4EHSD17B10 | |
| SCHEMBL18208197 | 0.79 | IRAK4 (0.48) | KDM4EHSD17B10 | |
| SCHEMBL18208199 | 0.79 | IRAK4 (0.48) | KDM4EHSD17B10 | |
| SCHEMBL18208638 | 0.78 | NTRK1 (0.41) | PDE4BHPGDCRHR1CRHR2NTRK1 | |
| SCHEMBL18208668 | 0.78 | KDM4E (0.47) | HPGDCRHR1CRHR2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078005-A1 | AMIDO-SUBSTITUTED AZASPIRO DERIVATIVES AS TANKYRASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |