Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103640 | 0.78 | CNR2 (0.35) | TLR9TLR8TLR7TRPV1 | |
| SCHEMBL20103485 | 0.74 | FFAR1 (0.42) | TLR9TLR8TLR7 | |
| SCHEMBL19561516 | 0.68 | CNR2 (0.34) | TRPV1 | |
| SCHEMBL20103476 | 0.64 | FFAR1 (0.41) | — | |
| SCHEMBL26621148 | 0.61 | CYP17A1 (0.30) | — | |
| SCHEMBL20642453 | 0.60 | TLR9 (0.36) | TLR9TLR8TLR7 | |
| SCHEMBL20103378 | 0.60 | CNR2 (0.34) | — | |
| SCHEMBL31676221 | 0.59 | TLR9 (0.36) | TLR9TLR8TLR7 | |
| SCHEMBL12166908 | 0.59 | SHBG (0.38) | — | |
| SCHEMBL6855924 | 0.59 | SHBG (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |