Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103371 | 0.80 | LNPEP (0.35) | LNPEP | |
| SCHEMBL20103360 | 0.73 | FFAR1 (0.35) | FFAR4 | |
| SCHEMBL21644893 | 0.73 | FFAR1 (0.35) | FFAR4 | |
| SCHEMBL20103378 | 0.73 | CNR2 (0.34) | FFAR4 | |
| SCHEMBL20103475 | 0.67 | FFAR1 (0.43) | — | |
| SCHEMBL8216851 | 0.64 | SLC6A2 (0.36) | — | |
| SCHEMBL21644839 | 0.64 | FFAR1 (0.54) | — | |
| SCHEMBL21688291 | 0.64 | FFAR1 (0.54) | — | |
| SCHEMBL21644838 | 0.64 | FFAR1 (0.54) | — | |
| SCHEMBL20103226 | 0.64 | FFAR1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |