Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103584 | 0.89 | FFAR1 (0.66) | FFAR1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL21644844 | 0.87 | FFAR1 (0.49) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL21644842 | 0.87 | FFAR1 (0.49) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL21644846 | 0.87 | FFAR1 (0.49) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL21688368 | 0.86 | FFAR1 (0.46) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20103443 | 0.86 | FFAR1 (0.44) | FFAR1POLB | |
| SCHEMBL20103446 | 0.86 | FFAR1 (0.44) | FFAR1POLB | |
| SCHEMBL20103527 | 0.86 | FFAR1 (0.44) | FFAR1POLB | |
| SCHEMBL21688395 | 0.85 | FFAR1 (0.43) | FFAR1L3MBTL1ALDH1A1 | |
| SCHEMBL21688298 | 0.84 | FFAR1 (0.43) | FFAR1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |