Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103672 | 0.89 | FFAR1 (0.57) | FFAR1POLBMEN1ALDH1A1MAPK1 | |
| SCHEMBL21645004 | 0.86 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL21645002 | 0.86 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL21644948 | 0.84 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL21644949 | 0.84 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL20103397 | 0.84 | FFAR1 (0.48) | FFAR1POLBMEN1ALDH1A1MAPK1 | |
| SCHEMBL29454631 | 0.83 | FFAR1 (0.58) | FFAR1KMT2A | |
| SCHEMBL23255992 | 0.83 | FFAR1 (0.60) | FFAR1MEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL21644928 | 0.83 | FFAR1 (0.48) | FFAR1 | |
| SCHEMBL21644927 | 0.83 | FFAR1 (0.48) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |