Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048992 | 0.90 | LPAR1 (0.35) | LPAR1LPAR5HCRTR2KLKB1HCRTR1 | |
| SCHEMBL17097660 | 0.90 | LPAR1 (0.35) | LPAR1LPAR5HCRTR2KLKB1HCRTR1 | |
| SCHEMBL17099186 | 0.88 | EGFR (0.36) | LPAR1LPAR5KLKB1MEN1KMT2A | |
| SCHEMBL17099185 | 0.88 | EGFR (0.36) | LPAR1LPAR5KLKB1MEN1KMT2A | |
| SCHEMBL17048970 | 0.86 | ALDH1A1 (0.34) | LPAR1LPAR5HCRTR2MEN1KMT2A | |
| SCHEMBL17048972 | 0.86 | ALDH1A1 (0.34) | LPAR1LPAR5HCRTR2MEN1KMT2A | |
| SCHEMBL17098141 | 0.86 | ALDH1A1 (0.35) | LPAR1LPAR5KLKB1MEN1KMT2A | |
| SCHEMBL17098144 | 0.86 | ALDH1A1 (0.35) | LPAR1LPAR5KLKB1MEN1KMT2A | |
| SCHEMBL17097524 | 0.84 | POLB (0.35) | LPAR1LPAR5KLKB1MEN1KMT2A | |
| SCHEMBL17097522 | 0.84 | POLB (0.35) | LPAR1LPAR5KLKB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |