SCHEMBL20104481

SCHEMBL20104481

Bc1cnc(-c2nc3cc(C(F)(F)F)n(OC)c(=O)c3n2C)c(S(=O)(=O)CC)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 1/20 0.31
DDR1 Q08345 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20104518 0.90 DDR1 (0.33) LRRK2DDR1
SCHEMBL21577860 0.89 DDR1 (0.33) LRRK2DDR1
SCHEMBL23005342 0.87 LRRK2 (0.31) LRRK2
SCHEMBL31248462 0.85 DDR1 (0.31) LRRK2DDR1
SCHEMBL20104479 0.85 DDR1 (0.31) LRRK2DDR1
SCHEMBL20104431 0.84 DDR1 (0.34) DDR1
SCHEMBL23971562 0.84
SCHEMBL31248465 0.83
SCHEMBL20104522 0.83
SCHEMBL20104475 0.83 DDR1 (0.33) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018077565-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2018-05-03 WO disclosed