Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539304 | 0.90 | BRD4 (0.31) | LRRK2MCHR1 | |
| SCHEMBL20104518 | 0.88 | DDR1 (0.33) | LRRK2 | |
| SCHEMBL20104481 | 0.87 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL21577860 | 0.87 | DDR1 (0.33) | LRRK2 | |
| SCHEMBL23005340 | 0.86 | XPO1 (0.32) | MCHR1 | |
| SCHEMBL31248460 | 0.86 | XPO1 (0.32) | MCHR1 | |
| SCHEMBL31248462 | 0.83 | DDR1 (0.31) | LRRK2 | |
| SCHEMBL20104479 | 0.83 | DDR1 (0.31) | LRRK2 | |
| SCHEMBL31248465 | 0.83 | — | — | |
| SCHEMBL20104522 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053970-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053970-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | DDT, SHMT1, ACHE | LRRK2 558/4885MCHR1 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.