SCHEMBL2010471

SCHEMBL2010471

CC(=O)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.54
CYP19A1 P11511 3/20 0.53
BRD4 O60885 6/20 0.51
PTGDR2 Q9Y5Y4 1/20 0.51
MRGPRX4 Q96LA9 1/20 0.49
ESRRA P11474 1/20 0.48
F2 P00734 1/20 0.48
F10 P00742 1/20 0.48
PRSS1 P07477 1/20 0.48
F7 P08709 1/20 0.48
SMPD1 P17405 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
NPC1 O15118 1/20 0.48
AR P10275 1/20 0.48
HPGD P15428 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CREBBP Q92793 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5784623 0.96 MAOB (0.51) MAOBCYP19A1BRD4PTGDR2MRGPRX4
SCHEMBL23226755 0.91 CYP19A1 (0.54) CYP19A1BRD4MRGPRX4F2F10
SCHEMBL11091209 0.89 CYP19A1 (0.52) CYP19A1BRD4ESRRAF2F10
SCHEMBL15754360 0.89 SMN1; SMN2 (0.56) CYP19A1BRD4MRGPRX4ESRRAF2
SCHEMBL6074797 0.88 PTGDR2 (0.66) MAOBCYP19A1BRD4PTGDR2MRGPRX4
SCHEMBL6074264 0.88 CYP19A1 (0.51) CYP19A1BRD4ESRRAF2F10
SCHEMBL11671517 0.87 AR (0.52) MAOBCYP19A1BRD4PTGDR2MRGPRX4
SCHEMBL1221632 0.87 CYP19A1 (0.50) CYP19A1BRD4ESRRAF2F10
SCHEMBL10659205 0.87 CYP19A1 (0.50) CYP19A1BRD4ESRRAF2F10
Water SCHEMBL10641992 0.86 CYP19A1 (0.49) CYP19A1BRD4ESRRAF2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390668-A Compound with ketoxime ether structure and application thereof 复旦大学 2025-02-07 CN disclosed
US-11286235-B2 Ultra short acting anti-arrhythmic agents Academic Pharmaceuticals, Incorporated (US) 2022-03-29 US disclosed
US-11286235-B2 Ultra short acting anti-arrhythmic agents Academic Pharmaceuticals, Incorporated (US) 2022-03-29 US disclosed
US-20210107867-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS ACADEMIC PHARMACEUTICALS INCORPORATED 2021-04-15 US disclosed
US-20210107867-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS ACADEMIC PHARMACEUTICALS INCORPORATED 2021-04-15 US disclosed
US-10793519-B2 Ultra short acting anti-arrhythmic agents ACADEMIC PHARMACEUTICALS INCORPORATED (US) 2020-10-06 US disclosed
US-10793519-B2 Ultra short acting anti-arrhythmic agents ACADEMIC PHARMACEUTICALS INCORPORATED (US) 2020-10-06 US disclosed
US-20190352257-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS ACADEMIC PHARMACEUTICALS INCORPORATED 2019-11-21 US disclosed
US-20190352257-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS ACADEMIC PHARMACEUTICALS INCORPORATED 2019-11-21 US disclosed
US-7964628-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-06-21 US disclosed
US-5776983-A ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-07-07 US disclosed
WO-1997037646-A1 CATECHOLAMINE SURROGATES USEFUL AS β3 AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 1997-10-16 WO disclosed
EP-0659737-A2 Catecholamine surrogates useful as B3 agonists BRISTOL-MYERS SQUIBB COMPANY (US) 1995-06-28 EP disclosed
US-4753962-A HYPOGLYCEMIC, ANTIOBESITY AGENT BEECHAM GROUP P.L.C. (GB) 1988-06-28 US disclosed
US-4654371-A ANTI-OBESITY, HYPOGLYCEMIA AGENTS BEECHAM GROUP P.L.C. (GB) 1987-03-31 US disclosed
US-4478849-A HYPERGLYCEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1984-10-23 US disclosed
US-4473566-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-25 US disclosed
US-4254117-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-03-03 US disclosed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP disclosed
US-4143166-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190352257-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS SCN5A, CACNA1G, CACNA1H MAOB 2237/4885CYP19A1 3438/4885BRD4 2897/4885
US-20210107867-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS SCN5A, CACNA1G, CACNA1H MAOB 2237/4885CYP19A1 3438/4885BRD4 2897/4885
US-11286235-B2 Ultra short acting anti-arrhythmic agents SCN5A, CACNA1G, CACNA1H MAOB 2237/4885CYP19A1 3438/4885BRD4 2897/4885
US-10793519-B2 Ultra short acting anti-arrhythmic agents SCN5A, CACNA1G, CACNA1H MAOB 2237/4885CYP19A1 3438/4885BRD4 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.