SCHEMBL20104750

SCHEMBL20104750

NC1(C(CO)C(=O)O)CCCCCCCCCCC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
BLM P54132 1/20 0.35
CACNA2D1 P54289 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C19 P33261 2/20 0.33
TGFBR1 P36897 1/20 0.31
OR51E2 Q9H255 1/20 0.31
MME P08473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20104759 0.82 MME (0.39) TSHRUSP2ALDH1A1LMNACYP1A2
SCHEMBL20104799 0.80 USP2 (0.33) TSHRUSP2ALDH1A1LMNACYP1A2
SCHEMBL20104770 0.79 CYP1A2 (0.41) TSHRUSP2ALDH1A1LMNACYP1A2
SCHEMBL20104758 0.79 SLC7A5 (0.41) TSHRUSP2ALDH1A1LMNACYP1A2
SCHEMBL20104827 0.77 BLM (0.42) TSHRUSP2ALDH1A1LMNACYP1A2
SCHEMBL24012336 0.77
SCHEMBL20104772 0.76 GSR (0.44) TSHRUSP2ALDH1A1LMNACYP1A2
SCHEMBL20104715 0.73 SRR (0.47) LMNACYP1A2MME
SCHEMBL9605481 0.72 CYP2C19 (0.34) TSHRCYP2C19OR51E2MME
SCHEMBL24012312 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11195597-B2 Method and device for calculating acid dissociation constant, and program FUJITSU LIMITED (JP) 2021-12-07 US disclosed
US-20180121632-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM FUJITSU LIMITED (JP) 2018-05-03 US disclosed