Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254152 | 0.92 | SMN1; SMN2 (0.48) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 | |
| SCHEMBL23824133 | 0.91 | SMN1; SMN2 (0.49) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 | |
| SCHEMBL13028392 | 0.87 | SMN1; SMN2 (0.43) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 | |
| SCHEMBL29299819 | 0.87 | FOLH1 (0.51) | FOLH1SMN1; SMN2TP53 | |
| SCHEMBL24590552 | 0.87 | SMN1; SMN2 (0.50) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 | |
| SCHEMBL29299673 | 0.86 | FOLH1 (0.45) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 | |
| SCHEMBL29299828 | 0.85 | FOLH1 (0.48) | FOLH1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29299679 | 0.84 | ALDH1A1 (0.45) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 | |
| SCHEMBL26414594 | 0.84 | FOLH1 (0.43) | FOLH1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29299829 | 0.82 | SMN1; SMN2 (0.46) | FOLH1SMN1; SMN2TP53ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459565-B1 | SAXITOXIN DERIVATIVES, METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | UNIV LELAND STANFORD JUNIOR (US) | 2018-05-02 | — | — | EP | disclosed |