Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010536 | 1.00 | PTPN1 (0.58) | PTPN1HNF4APTPN6PTPN2TTR | |
| SCHEMBL2258403 | 0.84 | PTGS1 (0.46) | PTPN1HNF4ATTRSRD5A1SRD5A2 | |
| SCHEMBL9517755 | 0.81 | UNG (0.47) | PTPN1PTPN6PTPN2PTGS2NPC1 | |
| SCHEMBL29067760 | 0.80 | PTPN1 (0.73) | PTPN1HNF4APTPN6PTPN2TTR | |
| SCHEMBL1451927 | 0.79 | MCL1 (0.46) | PTPN1PTPN6PTPN2 | |
| SCHEMBL12339914 | 0.78 | PTPN1 (0.65) | PTPN1HNF4APTPN6PTPN2TTR | |
| SCHEMBL2009013 | 0.78 | RARA (0.43) | PTPN1PTPN6PTPN2L3MBTL1 | |
| SCHEMBL6437412 | 0.77 | F7 (0.41) | SRD5A2PTGS1L3MBTL1 | |
| SCHEMBL9519046 | 0.77 | RARA (0.39) | PTPN1PTPN6PTPN2 | |
| SCHEMBL2007016 | 0.74 | PTPN1 (0.35) | PTPN1HNF4APTPN6PTPN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | DNMT1, TET3, CTCF | PTPN1 4647/4885HNF4A 746/4885PTPN6 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.