Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 18/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20088550 | 0.91 | PDE10A (0.40) | PDE10ARECQLALDH1A1HTT | |
| SCHEMBL20106742 | 0.89 | PDE10A (0.34) | PDE10A | |
| SCHEMBL20088557 | 0.80 | PDE10A (0.36) | PDE10A | |
| SCHEMBL20088546 | 0.77 | PDE10A (0.42) | PDE10A | |
| SCHEMBL20106737 | 0.76 | PDE10A (0.37) | PDE10ARECQL | |
| SCHEMBL20088532 | 0.72 | PDE10A (0.39) | PDE10ARECQLALDH1A1HTT | |
| SCHEMBL20088552 | 0.68 | PDE10A (0.45) | PDE10A | |
| SCHEMBL20088556 | 0.67 | HRH4 (0.34) | PDE10A | |
| SCHEMBL20088648 | 0.67 | TRPA1 (0.36) | PDE10A | |
| SCHEMBL20088522 | 0.66 | TP53 (0.41) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080917-A1 | FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |