SCHEMBL20107159

SCHEMBL20107159

CCC(=O)NCC(=O)N/C=C\P

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PSMB5 P28074 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20107211 0.75 MEN1 (0.43) MEN1KMT2APSMB5
SCHEMBL20960533 0.73 KMT2A (0.50) MEN1KMT2APSMB5
SCHEMBL16802010 0.73 KMT2A (0.50) MEN1KMT2APSMB5
SCHEMBL12440112 0.69 MEN1 (0.50) MEN1KMT2APSMB5
SCHEMBL12838007 0.68 MEN1 (0.44) MEN1KMT2APSMB5
SCHEMBL95875 0.67
SCHEMBL23289286 0.67 MEN1 (0.48) MEN1KMT2APSMB5
SCHEMBL13291442 0.67
SCHEMBL23471380 0.67 MEN1 (0.48) MEN1KMT2APSMB5
SCHEMBL17574393 0.67 MEN1 (0.48) MEN1KMT2APSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018081367-A1 CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2018-05-03 WO disclosed