Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110302 | 0.84 | — | — | |
| SCHEMBL13973851 | 0.80 | MAPK1 (0.36) | TSHRALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL20107210 | 0.77 | TSHR (0.52) | MEN1KMT2APSMB5TSHRALDH1A1 | |
| SCHEMBL12838007 | 0.76 | MEN1 (0.44) | MEN1KMT2APSMB5ALDH1A1CYP2C9 | |
| Acetamide SCHEMBL2554283 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2ATSHRALDH1A1CYP2C9 | |
| SCHEMBL20107159 | 0.75 | MEN1 (0.40) | MEN1KMT2APSMB5 | |
| SCHEMBL19062814 | 0.75 | — | — | |
| SCHEMBL13291442 | 0.75 | — | — | |
| SCHEMBL9471990 | 0.72 | ALDH1A1 (0.34) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL12440112 | 0.72 | MEN1 (0.50) | MEN1KMT2APSMB5ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081367-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |