Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24025239 | 0.95 | CYP3A4 (0.51) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL25670454 | 0.92 | CYP3A4 (0.49) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL6909730 | 0.88 | CYP3A4 (0.64) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9306250 | 0.82 | CYP3A4 (0.49) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9306765 | 0.82 | CYP3A4 (0.49) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL25670482 | 0.78 | CYP3A4 (0.48) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL21732700 | 0.77 | CYP3A4 (0.44) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL10994346 | 0.76 | CYP3A4 (0.66) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL18193244 | 0.76 | CYP3A4 (0.42) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL8468797 | 0.76 | CYP3A4 (0.60) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066619-B2 | Phosphorous containing compounds and uses thereof | AFTON CHEMICAL CORPORATION (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200056114-A1 | Phosphorous Containing Compounds and Uses Thereof | AFTON CHEMICAL CORP (US) | 2020-02-20 | — | — | US | disclosed |
| WO-2018081822-A1 | PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | AFTON CHEMICAL CORPORATION (US) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200056114-A1 | Phosphorous Containing Compounds and Uses Thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885L3MBTL1 1962/4885TSHR 4882/4885 |
| US-11066619-B2 | Phosphorous containing compounds and uses thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885L3MBTL1 1962/4885TSHR 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.