Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107350 | 0.91 | CYP3A4 (0.38) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20107365 | 0.89 | CYP3A4 (0.37) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20107506 | 0.88 | CYP3A4 (0.38) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20107530 | 0.85 | — | — | |
| SCHEMBL20107296 | 0.85 | CYP3A4 (0.38) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL22240399 | 0.84 | CYP3A4 (0.35) | TSHRCYP3A4TDP1ATM | |
| SCHEMBL20107354 | 0.84 | CYP1A2 (0.33) | TSHRTDP1ALDH1A1 | |
| SCHEMBL22240312 | 0.80 | CYP3A4 (0.30) | TSHRCYP3A4TDP1ATM | |
| SCHEMBL20107344 | 0.79 | KDM4E (0.32) | TSHRTDP1ALDH1A1 | |
| SCHEMBL20107528 | 0.77 | CYP3A4 (0.37) | TSHRCYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133077-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | AFTON CHEMICAL CORP (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2018081822-A1 | PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | AFTON CHEMICAL CORPORATION (US) | 2018-05-03 | — | — | WO | disclosed |