Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107528 | 0.90 | CYP3A4 (0.37) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL20107527 | 0.88 | TSHR (0.43) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL22240399 | 0.88 | CYP3A4 (0.35) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL21732696 | 0.80 | CYP3A4 (0.44) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL20107529 | 0.80 | — | — | |
| SCHEMBL20107296 | 0.80 | CYP3A4 (0.38) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL20107350 | 0.80 | CYP3A4 (0.38) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL21732711 | 0.78 | CYP3A4 (0.42) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL22240391 | 0.78 | CYP3A4 (0.32) | CYP3A4TSHRATMTDP1L3MBTL1 | |
| SCHEMBL20107365 | 0.77 | CYP3A4 (0.37) | CYP3A4TSHRATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081822-A1 | PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | AFTON CHEMICAL CORPORATION (US) | 2018-05-03 | — | — | WO | disclosed |