Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 16/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17028248 | 0.80 | CYP11B1 (0.40) | ARMAOAMAOB | |
| SCHEMBL17028323 | 0.76 | MAP3K7 (0.39) | — | |
| SCHEMBL18854488 | 0.76 | GPR35 (0.37) | ARMAOBPGR | |
| SCHEMBL28937766 | 0.74 | AR (0.42) | ARPGR | |
| SCHEMBL20107708 | 0.74 | AR (0.35) | AR | |
| SCHEMBL29816290 | 0.74 | AR (0.35) | AR | |
| SCHEMBL20107968 | 0.73 | AR (0.39) | ARPGR | |
| SCHEMBL4739057 | 0.72 | AR (0.40) | ARPGR | |
| SCHEMBL6946088 | 0.72 | AR (0.46) | ARPGR | |
| SCHEMBL12128120 | 0.71 | AAK1 (0.49) | ARMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532468-B1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AG (DE) | 2022-03-23 | — | — | EP | disclosed |
| WO-2018077923-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |