Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | PYGL | P06737 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752119 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL2636634 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL5182602 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL8331267 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL4436406 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL9393271 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL1994118 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL240029 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL8509311 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E | |
| SCHEMBL31624452 | 1.00 | PDPK1 (0.43) | PDPK1GDAHIF1APYGLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096138-A2 | [18F]-FURANOSYLPURINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-11-11 | — | — | WO | claimed |
| US-20030068631-A1 | Method for the identification of synthetic cell-or tissue-specific transcriptional regulatory regions | BAYLOR COLLEGE OF MEDICINE | 2003-04-10 | — | — | US | claimed |
| US-6410228-B1 | DETERMINATING BINDING SITES | BAYLOR COLLEGE OF MEDICINE | 2002-06-25 | — | — | US | claimed |
| EP-1003911-A1 | METHOD FOR THE IDENTIFICATION OF SYNTHETIC CELL- OR TISSUE-SPECIFIC TRANSCRIPTIONAL REGULATORY REGIONS | Valentis Inc. (US) | 2000-05-31 | — | — | EP | claimed |
| WO-1999002737-A1 | METHOD FOR THE IDENTIFICATION OF SYNTHETIC CELL- OR TISSUE-SPECIFIC TRANSCRIPTIONAL REGULATORY REGIONS | VALENTIS, INC. (US) | 1999-01-21 | — | — | WO | claimed |
| WO-2011119901-A1 | GENE AMPLIFICATION AND TRANSFECTION METHODS AND REAGENTS RELATED THERETO | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-09-29 | — | — | WO | disclosed |
| US-7960536-B2 | Artificially generated promoter sequences for use in monitoring transcription factor binding; gene expression regulation | GENETRONICS, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-7749720-B2 | Methods of identifying compounds for producing insulin sensitization | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-06 | — | — | US | disclosed |
| EP-1963366-A4 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORP (US) | 2009-05-06 | — | — | EP | disclosed |
| US-20080227738-A1 | Compositions and methods for cell dedifferentiation and tissue regeneration | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2008-09-18 | — | — | US | disclosed |
| EP-1963366-A2 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORPORATION (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20080206252-A1 | Novel Polypeptides, and Nucleic Acids Encoding the Same | GENENTECH, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| WO-1993008296-A1 | OLIGONUCLEOTIDES HAVING CHIRAL PHOSPHORUS LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1993-04-29 | — | — | WO | disclosed |
| WO-1993007281-A1 | METHOD FOR GENETICALLY MODIFYING BONE MARROW CELLS OF PRIMATES, AND USEFUL CELLS THEREFOR THAT PRODUCE RECOMBINANT RETROVIRAL VECTORS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 1993-04-15 | — | — | WO | disclosed |
| WO-1992007080-A1 | A EUKARYOTIC EPISOMAL DNA CLONING AND EXPRESSION VECTOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-04-30 | — | — | WO | disclosed |
| US-4997926-A | Viricides | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0355135-A4 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES. | SCRIPPS CLINIC RES (US) | 1990-04-09 | — | — | EP | disclosed |
| EP-0355135-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0319206-A2 | Gene amplification | BERLEX LABORATORIES, INC. (US) | 1989-06-07 | — | — | EP | disclosed |
| WO-1989004662-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206252-A1 | Novel Polypeptides, and Nucleic Acids Encoding the Same | DDX21, PABPC4, UPF1 | PDPK1 4254/4885GDA 861/4885HIF1A 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.