SCHEMBL20108232

SCHEMBL20108232

CC/N=C\NCC[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](CCCNC(=N)N)N1C(=O)CNC1=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 10/20 0.48
▸ KISS1R Q969F8 6/20 0.46
▸ CCKBR P32239 2/20 0.45
▸ MC4R P32245 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108285 1.00 IL23R (0.48) IL23RKISS1RCCKBRMC4R
SCHEMBL19334761 0.92 IL23R (0.46) IL23RKISS1RCCKBRMC4R
SCHEMBL23430155 0.88 IL23R (0.50) IL23RKISS1RCCKBR
SCHEMBL23430154 0.88 IL23R (0.50) IL23RKISS1RCCKBR
SCHEMBL20108313 0.88 IL23R (0.49) IL23RKISS1RMC4R
SCHEMBL19334907 0.87 IL23R (0.46) IL23RKISS1RCCKBRMC4R
SCHEMBL20108376 0.86 MC4R (0.57) MC4R
SCHEMBL23430098 0.86 MC4R (0.59) MC4R
SCHEMBL20108543 0.84 IL23R (0.49) IL23RKISS1RCCKBR
SCHEMBL23430282 0.84 IL23R (0.49) IL23RKISS1RCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118784-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN IPSEN PHARMA S.A.S. (FR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118784-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN MC4R, MC3R, MC1R IL23R 420/4885KISS1R 87/4885CCKBR 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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