SCHEMBL19334907

CN/C=N\C=C\C[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](CS)N1C(=O)CNC1=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	4/20	0.46

▸	KISS1R	Q969F8	11/20	0.45

▸	MC4R	P32245	2/20	0.44

▸	NPBWR1	P48145	1/20	0.44

▸	CCKBR	P32239	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23430154	0.88	IL23R (0.50)	IL23RKISS1RCCKBR
SCHEMBL23430155	0.88	IL23R (0.50)	IL23RKISS1RCCKBR
SCHEMBL20108285	0.87	IL23R (0.48)	IL23RKISS1RMC4RCCKBR
SCHEMBL20108232	0.87	IL23R (0.48)	IL23RKISS1RMC4RCCKBR
SCHEMBL23430098	0.86	MC4R (0.59)	MC4R
SCHEMBL20108313	0.86	IL23R (0.49)	IL23RKISS1RMC4R
SCHEMBL23430286	0.84	KISS1R (0.49)	IL23RKISS1R
SCHEMBL23430118	0.83	IL23R (0.51)	IL23RKISS1RMC4RNPBWR1CCKBR
SCHEMBL20108376	0.82	MC4R (0.57)	MC4R
SCHEMBL19334761	0.81	IL23R (0.46)	IL23RKISS1RMC4RCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9758549-B2	Melanocortin receptor ligands modified with hydantoin	IPSEN PHARMA S.A.S. (FR)	2017-09-12	—	—	US	disclosed