Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 7/20 | 0.53 |
| ▸ | FABP3 | P05413 | 5/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426820 | 0.88 | TSHR (0.50) | FABP4FABP3CYP2A6ALDH1A1TSHR | |
| SCHEMBL30396794 | 0.85 | TSHR (0.47) | FABP4FABP3CYP2A6PTGS1PTGS2 | |
| SCHEMBL14860351 | 0.84 | GRIA1 (0.51) | FABP4FABP3GRIA1CACNG8PTGS2 | |
| SCHEMBL28388638 | 0.83 | TAAR1 (0.48) | FABP4GRIA1CACNG8ALDH1A1TSHR | |
| SCHEMBL27662017 | 0.83 | TAAR1 (0.48) | FABP4GRIA1CACNG8ALDH1A1TSHR | |
| SCHEMBL308199 | 0.83 | CYP2A6 (0.55) | FABP4FABP3GRIA1CACNG8CYP2A6 | |
| SCHEMBL13550138 | 0.83 | GRIA1 (0.50) | FABP4FABP3GRIA1CACNG8ALDH1A1 | |
| SCHEMBL27930519 | 0.82 | FABP3 (0.41) | FABP4FABP3CYP2A6PTGS1PTGS2 | |
| SCHEMBL28146320 | 0.81 | GRIA1 (0.49) | FABP4FABP3GRIA1CACNG8ALDH1A1 | |
| SCHEMBL22357781 | 0.81 | RAB9A (0.50) | FABP4FABP3GRIA1CACNG8CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104031005-B | A kind of preparation method of S-1574 intermediate | Jinan Chenghuishuangda Chemical Industry Co.,Ltd. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-102977053-B | Preparation method of tianeptine sodium impurity D | SHANDONG CHENGCHUANG PHARMACEUTICAL R & D CO LTD | 2015-04-15 | — | — | CN | claimed |
| CN-104031005-A | Method for preparing tianeptine sodium intermediate | JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD | 2014-09-10 | — | — | CN | claimed |
| CN-108135866-A | Carboxyl diaryl sulphur azepine amine is as μ-opioid receptor agonist | 哥伦比亚大学董事会 | 2018-06-08 | — | — | CN | disclosed |
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |
| CN-106535901-A | A new class of mu-opioid receptor agonists | 哥伦比亚大学董事会 | 2017-03-22 | — | — | CN | disclosed |
| CN-104031005-B | A kind of preparation method of S-1574 intermediate | Jinan Chenghuishuangda Chemical Industry Co.,Ltd. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-104031005-B | A kind of preparation method of S-1574 intermediate | Jinan Chenghuishuangda Chemical Industry Co.,Ltd. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-102977053-B | Preparation method of tianeptine sodium impurity D | SHANDONG CHENGCHUANG PHARMACEUTICAL R & D CO LTD | 2015-04-15 | — | — | CN | disclosed |
| CN-104031005-A | Method for preparing tianeptine sodium intermediate | JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD | 2014-09-10 | — | — | CN | disclosed |