SCHEMBL20108876

SCHEMBL20108876

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc(-c3ccc4ccc5ccc(-c6ccccc6)nc5c4n3)cc2)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 2/20 0.46
PARP1 P09874 1/20 0.38
CLK2 P49760 2/20 0.33
HIPK1 Q86Z02 2/20 0.33
HIPK2 Q9H2X6 2/20 0.33
HIPK3 Q9H422 2/20 0.33
CLK4 Q9HAZ1 2/20 0.33
CLK1 P49759 1/20 0.33
PIM1 P11309 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
ACACA Q13085 3/20 0.32
CYP2C9 P11712 1/20 0.32
MEN1 O00255 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNA5 P22460 1/20 0.32
DYRK2 Q92630 1/20 0.32
AR P10275 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108871 0.93 TOP1 (0.41) TOP1PARP1PIM1PIM2CYP2C9
SCHEMBL20108875 0.92 TOP1 (0.41) TOP1PARP1PIM1PIM2CYP2C9
SCHEMBL20108866 0.92 TOP1 (0.42) TOP1PARP1CYP2C9CYP3A4
SCHEMBL20108904 0.90 TOP1 (0.41) TOP1CYP2C9MEN1RAB9AKMT2A
SCHEMBL20108861 0.89 TOP1 (0.41) TOP1PARP1PIM1PIM2CYP2C9
SCHEMBL20108849 0.83 TOP1 (0.37) TOP1PARP1KCNA5CYP3A4
SCHEMBL20250354 0.83 PARP1 (0.46) TOP1PARP1CLK2HIPK1HIPK2
SCHEMBL17403775 0.81 PARP1 (0.46) TOP1PARP1PIM1PIM2MEN1
SCHEMBL20108868 0.81 TOP1 (0.41) TOP1CYP2C9MEN1KMT2ACYP3A4
SCHEMBL21122451 0.81 TOP1 (0.41) TOP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX TOP1 2172/4885PARP1 2652/4885CLK2 3450/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX TOP1 2172/4885PARP1 2652/4885CLK2 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.