Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010922 | 1.00 | DPP4 (0.33) | DPP4ALDH1A1TSHR | |
| SCHEMBL1336381 | 0.83 | DPP4 (0.36) | DPP4ALDH1A1 | |
| Bicarbonate SCHEMBL11385004 | 0.81 | DPP4 (0.35) | DPP4ALDH1A1 | |
| SCHEMBL19391257 | 0.74 | DPP4 (0.31) | DPP4ALDH1A1 | |
| SCHEMBL11120681 | 0.74 | ALDH1A1 (0.33) | DPP4ALDH1A1TSHR | |
| SCHEMBL29956950 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3766237 | 0.72 | DPP4 (0.39) | DPP4 | |
| SCHEMBL8508470 | 0.71 | DPP4 (0.33) | DPP4 | |
| SCHEMBL9638700 | 0.71 | — | — | |
| SCHEMBL7053316 | 0.70 | DPP4 (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173949-B2 | Dendritic high-molecular-weight polymer drug carriers and their conjugates with drugs especially for treatment of solid tumours | USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. (CZ) | 2015-11-03 | — | — | US | disclosed |
| EP-2512521-B1 | DENDRITIC HIGH-MOLECULAR-WEIGHT POLYMER DRUG CARRIERS AND THEIR CONJUGATES WITH DRUGS ESPECIALLY FOR TREATMENT OF SOLID TUMOURS | USTAV MAKROMOLEKULARNI CHEMIE (CZ) | 2014-02-26 | — | — | EP | disclosed |
| US-20120296048-A1 | Dendritic High-molecular-weight Polymer Drug Carriers and Their Conjugates with Drugs Especially for Treatment of Solid Tumours | MIKROBIOLOGICKY USTAV AV CR, V.V.I. (CZ) | 2012-11-22 | — | — | US | disclosed |
| EP-2512521-A2 | DENDRITIC HIGH-MOLECULAR-WEIGHT POLYMER DRUG CARRIERS AND THEIR CONJUGATES WITH DRUGS ESPECIALLY FOR TREATMENT OF SOLID TUMOURS | Ustav Makromolekularni Chemie AV CR, V.V.I. (CZ) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072627-A2 | DENDRITIC HIGH-MOLECULAR-WEIGHT POLYMER DRUG CARRIERS AND THEIR CONJUGATES WITH DRUGS ESPECIALLY FOR TREATMENT OF SOLID TUMOURS | USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. (CZ) | 2011-06-23 | — | — | WO | disclosed |