Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876024 | 0.82 | CYP1A2 (0.48) | MAOAKDM1AHTR2CHTR2BMAOB | |
| SCHEMBL30355340 | 0.71 | HTR2C (0.43) | HDAC4HDAC2HDAC8SLC5A2HTT | |
| SCHEMBL21711525 | 0.71 | HTR2C (0.43) | HDAC4HDAC2HDAC8SLC5A2HTT | |
| SCHEMBL27948099 | 0.69 | NPC1 (0.48) | MAOAHDAC4HDAC2HDAC8SLC5A2 | |
| SCHEMBL7005495 | 0.68 | KDM1A (0.68) | MAOAKDM1AHTR2CMAOB | |
| SCHEMBL7005493 | 0.68 | KDM1A (0.68) | MAOAKDM1AHTR2CMAOB | |
| SCHEMBL24593954 | 0.68 | CTRB1 (0.39) | HDAC4HDAC2HDAC8SLC5A2ALDH1A1 | |
| SCHEMBL9429108 | 0.68 | HTR2A (0.44) | MAOAHDAC4HDAC2HDAC8SLC5A2 | |
| SCHEMBL12676483 | 0.68 | MAPT (0.69) | HDAC4HDAC2HDAC8HTR2AHTR2C | |
| SCHEMBL8533570 | 0.66 | CYP1A2 (0.43) | MAOAKDM1AHTR2CHTR2BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137573-A1 | HERBICIDAL COMPOSITIONS COMPRISING, AND METHODS OF USE OF, HERBICIDALLY ACTIVE PYRANDIONES | SYNGENTA LIMITED (US) | 2013-05-30 | — | — | US | disclosed |
| EP-2523555-A2 | HERBICIDAL COMPOSITIONS COMPRISING, AND METHODS OF USE OF, HERBICIDALLY ACTIVE PYRANDIONES | Syngenta Limited (GB) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011073616-A2 | HERBICIDAL COMPOSITIONS COMPRISING, AND METHODS OF USE OF, HERBICIDALLY ACTIVE PYRANDIONES | SYNGENTA LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137573-A1 | HERBICIDAL COMPOSITIONS COMPRISING, AND METHODS OF USE OF, HERBICIDALLY ACTIVE PYRANDIONES | FOXM1, ARSA, RPS21 | MAOA 1230/4885HDAC4 1165/4885HDAC2 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.