⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793131 | 0.81 | MEN1 (0.36) | — | |
| SCHEMBL14775288 | 0.80 | — | — | |
| SCHEMBL10841112 | 0.78 | — | — | |
| SCHEMBL12667803 | 0.75 | TSHR (0.40) | — | |
| SCHEMBL30180013 | 0.73 | — | — | |
| SCHEMBL7790689 | 0.73 | — | — | |
| SCHEMBL10532348 | 0.72 | EP300 (0.52) | — | |
| SCHEMBL14115627 | 0.71 | PAM (0.35) | — | |
| SCHEMBL28596922 | 0.70 | EP300 (0.55) | — | |
| SCHEMBL28526728 | 0.70 | EP300 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118661-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Resilio Therapeutics, LLC | 2018-05-03 | — | — | US | disclosed |