SCHEMBL2011

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2231	0.91	MEN1 (0.40)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL17265475	0.91	LPAR1 (0.43)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL7482	0.90	TACR1 (0.39)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL1728	0.88	LPAR1 (0.52)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL2059	0.88	LPAR1 (0.52)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL1855	0.88	LPAR1 (0.44)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL1308	0.87	LPAR1 (0.43)	LPAR1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL6805	0.87	LPAR1 (0.42)	LPAR1LPAR3ANO1EGLN1NR1H4
	SCHEMBL6423	0.86	MEN1 (0.38)	ANO1TACR1EGLN1MEN1KMT2A
	SCHEMBL2240	0.85	LPAR1 (0.42)	LPAR1ABCC3ABCC4ABCB11CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.