SCHEMBL2231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2011	0.91	LPAR1 (0.44)	MEN1KMT2ALMNALPAR1ABCC3
	SCHEMBL17265474	0.91	MEN1 (0.37)	MEN1KMT2ANPSR1LMNATSHR
	SCHEMBL6423	0.89	MEN1 (0.38)	MEN1KMT2ANPSR1LMNAANO1
	SCHEMBL1879	0.88	KMT2A (0.40)	MEN1KMT2ANPSR1LMNATSHR
	SCHEMBL1245	0.88	ABCC3 (0.43)	NPSR1LPAR1ABCC3ABCC4ABCB11
	SCHEMBL1786	0.88	ABCC3 (0.43)	NPSR1LPAR1ABCC3ABCC4ABCB11
	SCHEMBL1678	0.87	MEN1 (0.39)	MEN1KMT2ANPSR1LMNATSHR
	SCHEMBL7482	0.86	TACR1 (0.39)	MEN1KMT2ALMNALPAR1ABCC3
	SCHEMBL6659	0.86	MEN1 (0.40)	MEN1KMT2ANPSR1TDP1ANO1
	SCHEMBL6868	0.84	FFAR1 (0.40)	MEN1KMT2ATDP1ANO1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.