Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889149 | 0.94 | POLB (0.45) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL157502 | 0.90 | POLB (0.48) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL30800968 | 0.90 | POLB (0.48) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL20110391 | 0.87 | KDM4E (0.34) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL4205858 | 0.86 | POLB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13878666 | 0.86 | POLB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL534652 | 0.86 | POLB (0.50) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL24469748 | 0.86 | PDK2 (0.40) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL4251695 | 0.85 | POLB (0.45) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL534807 | 0.85 | POLB (0.53) | POLBAPEX1HTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119014-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL POLYMERIZED FILMS | JNC CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180119014-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL POLYMERIZED FILMS | NAP1L1, CCNA1, NAP1L4 | POLB 1874/4885APEX1 1464/4885HTT 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.