Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 13/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534807 | 0.96 | POLB (0.53) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL14889149 | 0.92 | POLB (0.45) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL157502 | 0.91 | POLB (0.48) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL30800968 | 0.91 | POLB (0.48) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL13878666 | 0.86 | POLB (0.44) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL4205858 | 0.86 | POLB (0.44) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL20110392 | 0.86 | POLB (0.41) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL4251695 | 0.85 | POLB (0.45) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL4953296 | 0.84 | POLB (0.40) | POLBAPEX1HTTTDP1PDK2 | |
| SCHEMBL24469748 | 0.84 | PDK2 (0.40) | POLBAPEX1HTTTDP1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415794-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | Showa Denko K.K. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120010361-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | SHOWA DENKO K.K. (JP) | 2012-01-12 | — | — | US | disclosed |