Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20110460 | 0.88 | CYP3A4 (0.62) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL18095579 | 0.87 | CYP3A4 (0.70) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL20110449 | 0.87 | CYP3A4 (0.69) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL12227035 | 0.86 | CYP3A4 (0.80) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL20110436 | 0.86 | CYP3A4 (0.80) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL12572433 | 0.86 | CYP3A4 (0.80) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL20110443 | 0.86 | CYP3A4 (0.80) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL20110448 | 0.86 | CYP3A4 (0.80) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL18095577 | 0.86 | CYP3A4 (0.66) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 | |
| SCHEMBL21335031 | 0.84 | CYP3A4 (0.69) | CYP3A4CYP2C9P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118776-A1 | NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF | QUIMICA SINTETICA S.A. (ES) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118776-A1 | NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF | MTAP, PNP, UMPS | CYP3A4 347/4885CYP2C9 1702/4885P2RY2 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.