Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | HTT | P42858 | 12/20 | 0.54 |
| ▸ | MITF | O75030 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452248 | 0.85 | ALDH1A1 (0.64) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL6405505 | 0.83 | HTT (0.57) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL10876189 | 0.81 | HTT (0.55) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL9194366 | 0.81 | HTT (0.55) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL29451993 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL9827518 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL9234092 | 0.76 | HTT (0.57) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL9763242 | 0.76 | HTT (0.55) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL14574536 | 0.76 | HTT (0.56) | ALDH1A1HTTMITFSMN1; SMN2NPC1 | |
| SCHEMBL10360715 | 0.74 | HTT (0.54) | ALDH1A1HTTMITFSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119069-A1 | REACTIVE LEUCO COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | THE PROCTER & GAMBLE COMPANY | 2018-05-03 | — | — | US | disclosed |