SCHEMBL20111048

SCHEMBL20111048

O=C1C(=CC=C(C=Cc2c(O)n(-c3ccccc3)c(=O)n(-c3ccccc3)c2=O)c2ccccc2)C(=O)N(c2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.47
▸ KDM4E B2RXH2 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ CASP7 P55210 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ ITGA4 P13612 1/20 0.32
▸ ITGB7 P26010 1/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.31
▸ GSK3A P49840 1/20 0.30
▸ GSK3B P49841 1/20 0.30
▸ LMNA P02545 2/20 0.30
▸ POLB P06746 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ NTSR1 P30989 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111071 0.92 KMT2A (0.42) KMT2A
SCHEMBL12153783 0.83 KMT2A (0.54) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL23432909 0.75 MAPT (0.45) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL23432910 0.71 MEN1 (0.42) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL23432911 0.68 KMT2A (0.39) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL23433008 0.67 KMT2A (0.42) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL13109102 0.67 ITGA4 (0.39) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL23433042 0.64 KMT2A (0.35) KMT2AKDM4EMEN1ALDH1A1HPGD
SCHEMBL13943821 0.64 MAPT (0.46) KMT2AKDM4EMEN1ALDH1A1MAPT
SCHEMBL13109101 0.62 MAPT (0.46) KMT2AKDM4EMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163711-A1 LENS FOR SPECTACLES AND SPECTACLES FUJIFILM CORPORATION (JP) 2021-06-03 — — US disclosed
US-10711082-B2 Near infrared absorbing colorant polymer, composition, film, optical filter, pattern forming method, and device FUJIFILM CORPORATION (JP) 2020-07-14 — — US disclosed
US-10598835-B2 Infrared absorbing composition, infrared cut filter, laminate, pattern forming method, solid image pickup element FUJIFILM CORPORATION (JP) 2020-03-24 — — US disclosed
US-20180120485-A1 INFRARED ABSORBING COMPOSITION, INFRARED CUT FILTER, LAMINATE, PATTERN FORMING METHOD, SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2018-05-03 — — US disclosed
US-20180118865-A1 NEAR INFRARED ABSORBING COLORANT POLYMER, COMPOSITION, FILM, OPTICAL FILTER, PATTERN FORMING METHOD, AND DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 — — US disclosed
Send feedback