Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20106701 | 0.86 | CA1 (0.33) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL3599378 | 0.83 | LPL (0.41) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL21603503 | 0.80 | LPL (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL153708 | 0.78 | LPL (0.38) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL21509781 | 0.78 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL18332596 | 0.78 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL20661010 | 0.76 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL24576537 | 0.74 | PDGFRB (0.43) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14532177 | 0.73 | LPL (0.41) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16494801 | 0.72 | ESR2 (0.35) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080918-A1 | 3-ARYL-2H-PYRAZOLO[4,3-B]PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |
| WO-2018080916-A1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |