Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20085916 | 0.88 | ADORA2A (0.38) | ADORA2ATRPA1 | |
| SCHEMBL20088953 | 0.87 | TRPA1 (0.45) | ADORA2ATRPA1 | |
| SCHEMBL20112873 | 0.87 | ADORA2A (0.35) | ADORA2A | |
| SCHEMBL20085906 | 0.86 | ADORA2A (0.35) | ADORA2ATRPA1 | |
| SCHEMBL20085927 | 0.86 | ADORA2A (0.37) | ADORA2ATRPA1 | |
| SCHEMBL20089087 | 0.86 | ADORA2A (0.35) | ADORA2ATRPA1 | |
| SCHEMBL20088890 | 0.86 | ADORA2A (0.37) | ADORA2ATRPA1 | |
| SCHEMBL20085923 | 0.85 | ADORA2A (0.33) | ADORA2ATRPA1 | |
| SCHEMBL20088897 | 0.85 | ADORA2A (0.34) | ADORA2ATRPA1 | |
| SCHEMBL20088957 | 0.81 | TRPA1 (0.38) | ADORA2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532476-B1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-19 | — | — | EP | claimed |
| EP-3532476-B1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-19 | — | — | EP | disclosed |
| WO-2018080916-A1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |